The initial symptoms of fifth disease are very general. They often include:
- low-grade fever
- sore throat
After a few days of having these symptoms, most young people develop a red rash that first appears on the cheeks. The rash often spreads to the arms, legs, and trunk of the body within a few days. The rash may last for weeks, but usually by the time you see it you’re no longer contagious.
The rash is more likely to appear in children than in adults with fifth disease. In fact, the main symptom adults usually experience is joint pain. The joint pain can last for several weeks and is usually most prominent in the wrists, ankles, and knees.